Cardiolipin Antibody, IgA
Also known as: CARDIO IGA
Use
Cardiolipin Antibody, IgA testing is used in the evaluation of patients suspected of having Antiphospholipid Syndrome (APS), especially when seronegative. It aids in the diagnosis by identifying IgA antibodies against cardiolipin, which are phospholipids associated with APS. This assay is particularly useful in conjunction with other non-criteria antiphospholipid antibody tests to provide a more comprehensive assessment of APS risk.
Special Instructions
Not provided.
Limitations
This test is specifically for the detection of IgA class cardiolipin antibodies and may not detect other antiphospholipid antibodies important in APS diagnosis. It is not intended to replace clinical judgment and should be considered as part of a comprehensive diagnostic approach. False positives or negatives can occur due to interfering substances or improper specimen handling.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 5076-5 - Cardiolipin IgA Ser IA-aCnc
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Collect using a serum separator tube. Separate serum from cells ASAP or within 2 hours of collection and transfer to an ARUP standard transport tube.
Storage Instructions
Store and transport refrigerated. Ambient stability is 48 hours. Refrigerated stability is 2 weeks. Frozen stability is 1 year, avoiding repeated freeze/thaw cycles.
Causes for Rejection
Plasma or other body fluids, contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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