Chromosome Analysis, Leukemic Blood

Casandra

Casandra Test Code AR45563Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2002290CPT Codes 88237, 88264, 88299

Chromosome Analysis, Leukemic Blood

Also known as: CHR LKB

Clinical Use

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Use

The Chromosome Analysis, Leukemic Blood test is used for the diagnosis, prognosis, and monitoring of hematopoietic neoplasms, particularly in cases where bone marrow is unavailable for cytogenetic studies. The test is pivotal in oncology studies, particularly for acute lymphoblastic leukemia (ALL), myeloproliferative neoplasms (MPNs), chronic lymphocytic leukemia (CLL), and myelodysplastic syndromes. It provides critical information by identifying chromosomal abnormalities that might influence treatment decisions and clinical outcomes.

Special Instructions

This test must be ordered using the Oncology test request form (#43099) or through your ARUP interface. It's crucial to indicate if the patient has received a bone marrow transplant and to specify the sex of the donor when ordering. The test information must be provided with the order to ensure appropriate culturing and reporting. Specimens enrolled in external studies requiring additional work-up may incur additional charges.

Limitations

The test involves culturing living cells, which means turnaround times are subject to variability. Frozen or clotted specimens are unacceptable as they compromise the integrity of cell cultures necessary for accurate chromosome analysis. As a laboratory-developed test (LDT), it has not been cleared or approved by the FDA, but is performed in a CLIA certified lab for clinical purposes.

Test Details

New York Approved