Coccidioides Antibodies Reflexive Panel, Serum
Also known as: COCCI R
Use
Coccidioides Antibodies Reflexive Panel, Serum aids in the diagnosis of coccidioidomycosis, a fungal infection caused by Coccidioides species. The test includes screening by immunoassay (IgM and IgG) and confirmation by complement fixation and immunodiffusion. Positive or equivocal results in immunoassay prompts reflexive testing with additional methods to improve diagnostic accuracy, helping distinguish acute from chronic or previous infections.
Special Instructions
If the immunoassay testing is equivocal or positive for IgM and/or IgG, then Coccidioides Antibodies by Immunodiffusion and Coccidioides Antibody Titer by Complement Fixation will be added. Additional charges apply for reflex testing. Mark specimens plainly as "acute" or "convalescent" for appropriate interpretation.
Limitations
Testing is limited to serum samples only; other body fluids are unacceptable. Hemolysis, lipemia, or contamination of specimens may affect results or cause rejection of the sample. The presence of IgM and IgG antibodies aids in diagnosis, but antibodies might not be detectable in all infected individuals, especially in the early stages or in immunocompromised patients. Immunodiffusion and complement fixation tests are more specific but may not reach sufficient sensitivity for detecting all cases.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 90448-2
- 27009-0
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.6 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect using Serum Separator Tube (SST). Separate from cells as soon as possible or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, hemolyzed, icteric, or lipemic specimens. Other body fluids.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
Other tests from different labs that may be relevant