Cryptococcus Antigen
Use
Aid in establishing the presence of Cryptococcus neoformans or Cryptococcus gattii infection
Special Instructions
Reflex to titer on positive result. Ensure consistent use of the same assay for monitoring patients with positive cryptococcal antigen results due to potential variations in endpoint titers between different testing methods.
Limitations
Endpoint titers may not correlate between different methods of cryptococcal antigen testing. Patients should be monitored with the same assay if antigen results are positive. False-positive results due to rheumatoid factor have not been observed. A negative test does not rule out Cryptococcus infection, especially if only a single specimen is tested and symptoms of cryptococcosis are present.
Methodology
Immunoassay (Lateral Flow)
Biomarkers
LOINC Codes
- 70910-5
- 70910-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Storage Instructions
Refrigerated (2°-8°C) or frozen (<−20°C)
Causes for Rejection
Quantity not sufficient for analysis; inappropriate specimen source; inappropriate specimen collection device; hemolysis; lipemia; specimen stability exceeded; name discrepancy between the name on the specimen container and the name in the computer or on the test request form
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 72 hours |
| Frozen | >72 hours |
Other tests from different labs that may be relevant