FISH, Interphase, CD138+ Cells

Casandra

Casandra Test Code AR31909Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3002737CPT Codes 88271, 88275

FISH, Interphase, CD138+ Cells

Also known as: FISHICD138

Clinical Use

Order Test

Use

This test is used for ordering individual or multiple FISH probes for patients with multiple myeloma. It identifies prognosis-specific genomic abnormalities by performing fluorescence in situ hybridization (FISH) on CD138+ sorted cells. The test is crucial for patients with multiple myeloma as it helps in assessing high-risk genomic features, which can correlate with prognosis and treatment strategies.

Special Instructions

Desired FISH probe and pertinent clinical diagnosis must be provided with the test order to avoid delays. This test must be ordered using Oncology test request form #43099 or through ARUP interface. If chromosome analysis is not performed at ARUP on the same sample, an additional processing fee for Bone Marrow/PBL Culture will apply. Multiple FISH tests on the same specimen will incur the culture fee only once.

Limitations

This test will not be performed unless the desired FISH probe and clinical diagnosis are provided. The sample prioritization for CD138+ cell sorting may impact chromosome analysis success. In cases where cell sorting does not yield enough cells, testing may be done on unsorted cells if available. Paraffin-embedded and clotted specimens are not acceptable. Ambient stability is 48 hours; refrigeration maintains stability for 48 hours, while freezing is not acceptable.

Test Details

New York Approved