FISH, MET Amplification
Also known as: Renal Cancer, Tyrosine Kinase, c-MET, NSCLC, Mesencymal Epithelial Transition Factor
Use
The proto‑oncogene MET (c‑MET) encodes a hepatocyte growth factor receptor with tyrosine‑kinase activity. Overexpression or amplification of MET has been observed in a variety of neoplasms, including kidney, lung, head and neck, ovary, breast, thyroid, brain, stomach, pancreas, and colon. MET gene amplification, detected by FISH, has been associated with unfavorable prognosis in non‑small cell lung cancer (NSCLC) and resistance to EGFR inhibitors.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Other tests from different labs that may be relevant