Use

Aids in the diagnosis of limbic encephalitis and autoimmune epilepsy. May be used to monitor treatment response in individuals who are antibody positive. The presence of GABA-AR antibodies may be associated with refractory seizures, memory loss, behavior changes, abnormal movements, and decreased level of consciousness. GABA-AR encephalitis may be paraneoplastic, but tumor type is variable (e.g., thymoma, small cell lung cancer, rectal cancers, and hematologic malignancy). GABA-AR encephalitis may also be associated with post-viral and autoimmune diseases.