Hemoglobinopathy Fractionation Cascade
Use
Diagnose thalassemias and hemoglobin variants
Special Instructions
When submitting the test request form, ensure that the patient's age, ethnic background, mean corpuscular volume (MCV), transfusion history, and any other pertinent hematological information are stated. This information aids in providing an accurate clinical assessment and interpretation of the results.
Limitations
The test may require repeated or additional confirmatory testing if initial screening shows abnormal results. Any abnormal findings from capillary electrophoresis necessitate further investigation through reflexive testing methods like HPLC and hemoglobin solubility tests, which may extend the turnaround time. Additionally, the test cannot be applied to hemolyzed samples, or samples that have been improperly stored for prolonged periods.
Methodology
Other
Biomarkers
LOINC Codes
- 43113-0
- 32682-7
- 20572-4
- 4552-6
- 32683-5
- 12710-0
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1.5 mL
Minimum Volume
0.8 mL
Container
Lavender-top (EDTA) tube
Collection Instructions
To avoid delays in turnaround time, please submit a separate lavender-top tube for each test requiring a lavender-top.
Patient Preparation
Fasting or fluid restriction is not necessary.
Storage Instructions
Refrigerate at 2°C to 8°C.
Causes for Rejection
Clotted specimen; aged, improperly stored blood samples
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant