Human Immunodeficiency Virus 1 (HIV-1) DNA Sequencing Protease−Reverse Transcriptase
Also known as: Cell-associated Viral DNA, HIV-1 Genotype, Resistance Analysis
Use
Detect resistance of HIV-1 to protease and reverse transcriptase inhibitors in cell-associated viral DNA.
Special Instructions
Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested. Testing schedules may vary, and additional time should be allowed for confirmatory or reflex tests.
Limitations
This procedure should be used for patients with documented HIV-1 infection and undetectable viral load or low level viremia. Careful interpretation of results is necessary, as the presence of resistance-associated mutations depends on several factors, including sampling time relative to antiretroviral therapy and the overall viral load.
Methodology
NGS
Biomarkers
LOINC Codes
- 80692-7
- 80695-0
- 80692-7
- 80694-3
Result Turnaround Time
10-14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube
Collection Instructions
Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen.
Storage Instructions
Freeze.
Causes for Rejection
Quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen
Other tests from different labs that may be relevant