Human Immunodeficiency Virus 1 (HIV-1) Trofile® Select
Also known as: Coreceptor Tropism (Phenotypic), HIV Coreceptor Tropism Phenotype, Tropism
Use
Trofile® Select allows for the determination of HIV-1 coreceptor tropism status, by which the appropriate assay, Trofile® or Trofile® DNA, is selected through an initial prescreening viral assessment. The coreceptor tropism status may be used to determine eligibility for CCR5 antagonist therapy, such as maraviroc (Selzentry®).
Special Instructions
Both frozen plasma and frozen whole blood are required for this profile. If both samples are not received, the order for the assay will be cancelled.
Limitations
This procedure should be used only for patients with documented HIV-1 infection.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 51969-4
- 50790-5
- 57182-8
- 77202-0
- 49549-9
- 75608-0
- 80690-1
- 62364-5
Result Turnaround Time
33-41 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA)
Collection Instructions
Centrifuge three tubes within six hours of collection. Remove plasma, transfer plasma to screw-cap polypropylene transport tubes, and freeze. Ship specimen frozen.
Storage Instructions
Freeze.
Causes for Rejection
Both frozen plasma and frozen whole blood not received; insufficient volume; heparinized plasma; specimen not frozen
Other tests from different labs that may be relevant