Human Immunodeficiency Virus Types 1 and 2 (HIV-1/2) Antibody Differentiation, Supplemental, With Reflex to HIV-1/HIV-2 by Qualitative NAAT

Casandra

Casandra Test Code AR03065Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2012669CPT Codes 86701, 86702, 87535, 87538

Human Immunodeficiency Virus Types 1 and 2 (HIV-1/2) Antibody Differentiation, Supplemental, With Reflex to HIV-1/HIV-2 by Qualitative NAAT

Also known as: HIV AB DIF

Clinical Use

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Use

Useful as a supplemental assay for repeatedly reactive third- or fourth-generation HIV screen tests when following the CDC's recommended HIV testing algorithm. This test discriminates between HIV-1 and HIV-2 antibodies and reports results for each type. It should not be used as a rapid screen or as a follow-up test for a positive rapid screen, nor for blood donor screening or HCT/P screening.

Special Instructions

This test is only for use when a patient has a repeatedly reactive third- or fourth-generation HIV screen test result. It is a part of a multitest algorithm recommended by the CDC and CLSI for HIV diagnosis. Additional charges apply if a reflex to the HIV-1/HIV-2 by Qualitative NAAT test is needed.

Limitations

Not suitable for blood donor screening, associated reentry protocols, or HCT/P screening. This test is not to be ordered as a rapid screen test. Negative or indeterminate results in the antibody differentiation immunoassay may trigger reflex testing by NAAT.

Test Details

New York Approved

Methodology

PCR-based

Biomarkers

2 components

HIV-1/2 Ab Differentiation ImmunoassayHuman Immunodeficiency Virus 1 and 2 (HIV-1/HIV-2) by Qualitative NAAT • Qualitative

LOINC Codes

Result Codes

77202-0
29893-5
30361-0
80203-3

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

3 mL

Minimum Volume

1.5 mL

Container

ARUP standard transport tube

Collection Instructions

Separate from cells within 24 hours of collection. Transfer 3 mL serum or plasma into an ARUP standard transport tube dedicated only for the HIV AB DIF assay. Remove particulate material. SHIP FROZEN.