Human Papillomavirus (HPV), Biopsy in situ Hybridization Subtypes (Tech Only)
Also known as: HPV by ISH
Use
Determine HPV type; confirm HPV infection; resolve cases with equivocal histopathology
Special Instructions
Not provided.
Limitations
The assay is limited to detecting the presence of six specific HPV viral types: HPV 6, 11, 16, 18, 31, and 33. It does not detect other HPV types. The results depend on the quality and quantity of the tissue sample submitted. Insufficient tissue or improper sample collection can invalidate results. The test is not FDA cleared or approved, indicating that its performance characteristics were established by LabCorp itself.
Methodology
Chromosomal / Cytogenetics (ISH)
Biomarkers
LOINC Codes
- 44551-0 - HPV DNA Tiss Ql Probe
- 77202-0 - Laboratory comment Report
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
One formalin-fixed, paraffin embedded (FFPE) tissue block or nine unstained positively charged slides
Minimum Volume
Six unstained tissue slides
Container
Paraffin block transport pouch or slide container
Collection Instructions
Tissue should be fixed in 10% neutral buffered formalin for no more than 72 hours. Embed in paraffin.
Storage Instructions
Room temperature
Causes for Rejection
Insufficient tissue; inappropriate tissue source; incorrect specimen type
Other tests from different labs that may be relevant