IGH‑CCND1 (BCL‑1/JH), Translocation, t(11;14) by PCR
Also known as: bcl-1/JH t(11;14)
Use
Bcl‑1/JH t(11;14) is highly specific for mantle cell lymphoma (MCL). The t(11;14) translocation is found in approximately 70% to 95% of MCL cases. The real‑time PCR assay can be used to monitor minimal residual disease in non‑Hodgkin lymphoma patients.
Special Instructions
Not provided.
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Methodology
PCR-based (PCR)
Biomarkers
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Lavender (EDTA) tube
Storage Instructions
Refrigerated transport
Causes for Rejection
Frozen specimens; clotted or grossly hemolyzed specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 1 year (if frozen) |
Other tests from different labs that may be relevant