LDL-P
Also known as: Low-density Lipoprotein Particle Number
Use
NMR LDL-P is a management tool used in appropriate high-risk patients (type 2 diabetes mellitus, metabolic syndrome, CVD risk equivalent, statin-treated patients) to adjudicate response to treatment and guide adjustment in therapy. It is used in conjunction with other lipid measurements and clinical evaluation to aid in the management of lipoprotein disorders associated with cardiovascular disease.
Special Instructions
The NMR LipoProfile® test is a blood test that directly measures the amount of LDL circulating in the body. Centrifuge specimen within two hours of collection at 1600 to 1800 xg for 10 to 15 minutes to separate serum/plasma from the red cells and to avoid red cell contamination during shipment. Do not open NMR LipoTube (black-and-yellow-top).
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. Centrifuging the specimen while still cold may negatively affect the migration of the gel to the serum/red cell interface and may increase the likelihood of specimens being contaminated with red cells during shipment. All specimens should be centrifuged by the client prior to shipment to Labcorp to ensure sample integrity.
Methodology
Other
Biomarkers
LOINC Codes
- 54434-6
- 54434-6
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
NMR LipoTube (black-and-yellow-top tube), plain red-top tube
Collection Instructions
Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Gently invert tube eight to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation.
Storage Instructions
Refrigerate all acceptable tube types as soon as possible after centrifugation and within 24 hours of collection. Keep refrigerated prior to shipment, and ship on frozen cool packs. Do not store at room temperature. Do not freeze the sample. Sample is stable refrigerated for 12 days.
Causes for Rejection
Unspun specimens; plasma/serum contaminated with red cells; citrated plasma (light blue-top tube); gross hemolysis; specimen received in inappropriate container; specimen stored at room temperature for more than a total preanalytical time of 24 hours; specimen more than 12 days old.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 12 days |
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