Lead, Urine

Casandra

Casandra Test Code AR75550Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0025060CPT Code 83655

Also known as: LEAD U

Clinical Use

Order Test

Use

This test is useful in the assessment of chronic lead exposure and monitoring chelation therapy. It helps in evaluating potential lead poisoning by quantifying the amount of lead excreted in urine over a specified time period. The test can be essential for individuals with occupational exposure to lead, or in those undergoing treatment to remove excess lead from the body.

Special Instructions

The test requires careful specimen collection to avoid contamination and ensure accurate results. Patients should discontinue certain supplements and medications upon physician advice to prevent interference. Collection should avoid periods soon after contrast media exposure.

Limitations

Urine samples collected soon after the administration of iodinated or gadolinium-based contrast media are not acceptable due to potential interference. The test may return falsely elevated results if collection containers are not certified to be trace element-free. Elevated results should be confirmed with a second specimen if contamination is suspected. Other factors such as improper collection method and contamination from skin or collection devices can affect results.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

Creatinine

Analyte

Creatinine, Urine - per volume • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Creatinine, Urine - per 24h • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Lead

Analyte

Lead, Urine - per 24h • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Lead, Urine - per volume • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Lead, Urine - ratio to CRT • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Result Codes

35674-1
2162-6
5677-0
30931-0
13466-8
19153-6
30211-7

Result Turnaround Time

1-5 days

Specimen

Urine

Volume

8 mL

Minimum Volume

1 mL

Container

ARUP Trace Element-Free Transport Tubes

Collection Instructions

24-hour or random urine collection in a plastic container. Record total volume and collection time on transport tube and test request form. Avoid collection within 72 hours after iodinated or gadolinium media exposure.

Patient Preparation

Discontinue non-essential supplements, vitamins, minerals upon physician advice. Avoid collection post-iodinated/gadolinium media exposure for 72 hours. For impaired kidney function, avoid collection for 14 days post-exposure.