Liver Cytosolic Antigen Type 1 (LC-1) Antibody, IgG
Also known as: LC-1
Use
The Liver Cytosolic Antigen Type 1 (LC-1) Antibody, IgG test is utilized to evaluate patients for autoimmune hepatitis of unknown etiology. It is recommended to be used in conjunction with the Liver-Kidney Microsome - 1 Antibody, IgG test, as part of a broader autoimmune liver disease testing algorithm. This test helps in identifying specific autoantibodies that are indicative of autoimmune hepatitis, which can assist in directing appropriate patient management and treatment strategies.
Special Instructions
This test is New York state approved, which indicates compliance with specific regulatory requirements for clinical laboratory testing within the state of New York. Users are encouraged to refer to ARUP Consult for assistance with test selection and interpretation related to autoimmune hepatitis and autoimmune liver diseases.
Limitations
While the LC-1 Antibody, IgG test is a useful tool for identifying autoimmune hepatitis, it should not be used as the sole diagnostic tool. False positives or negatives may occur, and results should be interpreted in conjunction with clinical findings and other laboratory tests. The presence of antibodies does not establish a diagnosis due to the overlap of autoimmune hepatitis markers with other liver diseases.
New York Approved
Methodology
Immunoassay (Western Blot)
Biomarkers
LOINC Codes
- 13175-5
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Serum Separator Tube
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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