Liver Fibrosis, Fibrosis‑4 (FIB‑4) Index Panel
Also known as: FIB4, NASH, NAFLD, Nonalcoholic, Fatty
Use
The FIB‑4 index is a simple non‑invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3‑F4). It serves as the preferred initial diagnostic assessment of metabolic dysfunction‑associated steatotic liver disease (MASLD) with liver fibrosis and helps determine need for additional assessment or referral to a specialist.
Special Instructions
Direct shipping arrangements must be made with the Central Lab specimen processing department due to short specimen stability. Specimen should be collected close to courier pickup. When ordering via SoftLab, include the comment "DIRECT SHIP - Sent to Quest SJC, CA" and specify Quest test code and specimen type in comments. This test code may also be aliased as REFLB.
Limitations
Not provided.
Methodology
Other
Biomarkers
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL serum (minimum 0.5 mL)
Minimum Volume
0.5 mL serum
Container
Serum Separator Tube (SST®)
Collection Instructions
Collect as close to courier pickup as possible; if multiple draw, lavender‑top last
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 5 days |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant