Casandra
Casandra Test Code QD57142Version 1 (DRAFT)
Performing Lab
Methylmalonic Acid, Urine with Creatinine
Also known as: MMA
Clinical Use
Order TestUse
Quantification of methylmalonic acid (MMA) in urine, normalized to creatinine, is used primarily to detect and monitor methylmalonic aciduria and functional vitamin B₁₂ (cobalamin) deficiency states, since methylmalonate accumulates when cobalamin is deficient.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Mass Spectrometry
Biomarkers
Creatinine
AnalyteCreatinine • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Methylmalonic Acid
AnalyteMethylmalonic Acid • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
LOINC Codes
Order Codes
- 14683‑7
Result Codes
- 25116‑5
Result Turnaround Time
6-10 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Urine
Volume
≥1.7 mL
Minimum Volume
0.6 mL
Container
Sterile container (urine cup)
Collection Instructions
Random clean‑catch urine, first‑void clean‑catch, catheterized urine, or 24‑hour urine; do not use preservative.
Causes for Rejection
Acidified urine; thawed urine.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 12 days |
| Frozen | 30 days |
Related Tests
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