Protein Electrophoresis With Interpretation, 24-Hour Urine
Also known as: Interpretation, Protein Electrophoresis, Urine
Use
Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.
Special Instructions
State the 24-hour volume on the request form for proper processing of the test.
Limitations
The test may not detect all proteinuria cases as the sensitivity of electrophoretic methods is limited. It also does not provide specific identification of anomalous proteins and is primarily used for screening elevated protein levels in urine rather than for detailed protein characterization.
Methodology
Other
Biomarkers
LOINC Codes
- 42482-0
- 77202-0
- 11502-2
- 49301-5
- 2888-6
- 2889-4
- 13986-5
- 13984-0
- 13987-3
- 13988-1
- 13989-9
- 42484-6
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
20-mL aliquot
Minimum Volume
6-mL aliquot
Container
12-mL plastic transport tube (Labcorp No. 23597) without preservative
Collection Instructions
Mix well.
Storage Instructions
Refrigerated (preferred) or room temperature
Causes for Rejection
Preservative added
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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