Protein Electrophoresis and Total Protein, Random Urine
Also known as: UPEP
Use
This test analyzes protein content in random urine, separating proteins into albumin, alpha‑1, alpha‑2, beta, and gamma components. Changes in levels or patterns can provide insight into inflammatory diseases, autoimmune conditions, various kidney injuries, plasma cell disorders, and cancers. It is especially useful when monoclonal gammopathy is suspected, or when elevated total protein, albumin, or immunoglobulin levels are detected. Results should be interpreted alongside other clinical, laboratory, and imaging data and may require follow‑up with bone marrow studies, serum protein electrophoresis, or immunofixation as needed.
Special Instructions
Not provided.
Limitations
Results should not be used in isolation; they are not sufficient alone for diagnosis or monitoring and should be evaluated with other clinical and laboratory findings. A 24‑hour urine electrophoresis test is preferred for definitive monitoring when indicated. Reflex tests such as immunofixation may incur additional charge.
Methodology
Other
Biomarkers
Result Turnaround Time
4-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
25 mL
Minimum Volume
15‑10 mL
Container
Sterile plastic urine container
Collection Instructions
Random urine; submit first morning void when possible; no preservative
Causes for Rejection
Acidified urine
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 5 days |
| Frozen | 30 days |
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