Varicella‑Zoster Virus Antibody (IgG)

Casandra

Casandra Test Code QD97442Version 1 (DRAFT)

Performing Lab

Lab Quest DiagnosticsLab Test ID 4439CPT Code 86787

Varicella‑Zoster Virus Antibody (IgG)

Also known as: Varicella IgG Antibodies, VZV IgG, Shingles, Herpes Zoster IgG Ab, Chicken Pox

Clinical Use

Order Test

Use

This test detects IgG-class antibodies to varicella‑zoster virus (VZV) and is useful for determining an individual’s immune status or aiding in the diagnosis of VZV infection. A positive IgG indicates the presence of antibodies; while it cannot distinguish between past and current infection, when active disease is not suspected, a positive result most likely indicates immunity from prior infection. However, vaccinated individuals may have lower antibody levels that might evade detection by this assay. (Quest Diagnostics FAQ)([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq117v1?utm_source=openai))

Special Instructions

Not provided.

Limitations

A positive IgG result cannot differentiate between active and past infection; interpretation requires clinical correlation including patient history and presentation. Additionally, antibody levels from vaccination may be lower than those from natural infection, possibly leading to false-negative results in vaccinated individuals. (Quest Diagnostics FAQ)([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq117v1?utm_source=openai))

Test Details