Casandra
Casandra Test Code AL45754Version 1 (DRAFT)
Performing Lab
Lab AllelicaLab Test ID N/A
AbsoluteDx Cardio
Clinical Use
Order TestUse
AbsoluteDx Cardio assesses hereditary cardiovascular disease risk, integrating monogenic variant interpretation and a Multi-Ancestry CAD PRS, evaluating risks tied to inherited cardiovascular conditions including Long QT syndrome and hypertrophic cardiomyopathy.
Special Instructions
Ordered via Allelica's secure process, using non-invasive saliva samples collected in-clinic or at home, sent to the laboratory for analysis.
Limitations
Risks estimations incorporate monogenic and polygenic data; potential inaccuracies exist tied to ancestry-specific thresholds and the scope of genomic data used.
Test Details
Methodology
NGS (WGS)
Biomarkers
Includes genetic variant analysis with low-coverage WGS and high-depth WES for robust cardiovascular disease risk assessment.
Mutation (42 genes)
LDLRAPOBPCSK9LDLRAP1FBN1TGFBR1TGFBR2SMAD3ACTA2MYH11PKP2DSPDSC2TMEM43DSG2RYR2CASQ2TRDNBAG3DESRBM20TNNC1TNNT2LMNAFLNCTTNCALM1CALM2CALM3COL3A1MYH7MYBPC3TNNI3TPM1MYL3ACTC1PRKAG2MYL2PLNKCNQ1KCNH2SCN5A
Result Turnaround Time
3-4 weeks
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Saliva
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Utilize non-invasive saliva collection methods for DNA extraction.