Adrenal Steroid Quantitative Panel by HPLC-MS/MS, Serum or Plasma
Also known as: ADSTEROID
Use
This test is used to detect the accumulation of specific steroids resulting from enzyme deficiencies in congenital adrenal hyperplasia (CAH). It is also used to monitor patients with CAH, providing insights into their adrenal steroid levels which impact various bodily functions including the stress response, immune system, and metabolic processes.
Special Instructions
Specimen should be collected in a serum separator tube; also acceptable are plain red, pink (K2EDTA), or green (sodium or lithium heparin) tubes. Separate serum or plasma from cells ASAP or within 2 hours and freeze immediately to maintain specimen integrity.
Limitations
The test is limited to detection of the steroids quantitatively. It does not determine the cause of enzyme deficiencies nor does it diagnose CAH directly. Results should be interpreted in the context of the clinical and laboratory findings. Refrigerated or room temperature specimens will not be accepted as they are deemed unacceptable due to potential degradation of the analytes.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 1657-6
- 1668-3
- 6765-2
- 2837-3
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.2 mL
Minimum Volume
0.6 mL
Container
ARUP standard transport tube
Collection Instructions
Use a serum separator tube. Separate serum or plasma from cells ASAP or within 2 hours, then freeze immediately.
Storage Instructions
CRITICAL FROZEN. Separate specimens must be submitted if multiple tests are ordered.
Causes for Rejection
Refrigerated or room temperature specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 6 months |
