Alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor (AMPAR) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF
Also known as: AMPA CSF
Use
This test aids in the diagnosis of limbic encephalitis. It can be used to monitor treatment response in individuals who are antibody positive. The presence of AMPA receptor antibodies may be associated with psychosis, with or without seizures. AMPA encephalitis can be paraneoplastic, although the type of associated tumor can vary, including thymic, lung, and breast cancer.
Special Instructions
If the Alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody, IgG by IFA with Reflex to Titer, CSF IgG is positive, an Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody Titer, IgG, CSF is reported with additional charges.
Limitations
A negative test result does not rule out a diagnosis of autoimmune encephalitis. Results should be interpreted in correlation with the patient's clinical history and other laboratory findings.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 82732-9
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer 0.5 mL CSF to an ARUP standard transport tube. (Min: 0.15 mL)
Storage Instructions
Refrigerated
Causes for Rejection
Hemolyzed, contaminated, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |