Buspirone Quantitative, Serum or Plasma
Also known as: BUSPIRON
Use
This test measures the concentration of buspirone in serum or plasma. Buspirone is an anxiolytic drug used to treat anxiety disorders. Monitoring the levels of buspirone can help ensure therapeutic efficacy and avoid toxicity. Buspirone concentration peaks in the plasma 40-90 minutes after oral administration, making timing of sample collection crucial for accurate interpretation of results.
Special Instructions
This testing is conducted at an NMS Labs facility, not ARUP, which requires separate specimens if multiple tests are requested. It is recommended to draw the sample 40-90 minutes post-dose to capture peak serum levels, which is vital for monitoring, as the buspirone level drops rapidly beyond this peak window.
Limitations
The test should not be performed using serum separator tubes, as these can yield inaccurate results. The presence of any specimen that doesn't meet the collection and handling protocols may cause rejection, which includes using a separator tube. It is crucial to follow the procedure properly to avoid false-negative results due to rapid drop in drug levels.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 9356-7
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tubes
Collection Instructions
Collect from plain red, lavender (EDTA) or pink (K2EDTA). Transfer 1 mL serum or plasma to ARUP Standard Transport Tubes.
Patient Preparation
Recommended peak draw 40-90 minutes post dose.
Storage Instructions
Store refrigerated, but samples are also acceptable at room temperature or frozen.
Causes for Rejection
Use of separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 month |
| Refrigerated | 1 month |
| Frozen | 4 months |
