Chromosome FISH, Interphase
Also known as: CHR FISHI
Use
Interphase fluorescence in situ hybridization (FISH) testing is utilized to detect specific chromosomal abnormalities in interphase cells. It aids in the evaluation of hematologic and oncologic conditions by identifying targeted probe abnormalities such as translocations, deletions, or amplifications to inform diagnosis and management.
Special Instructions
Not provided.
Limitations
Time required for testing may vary depending on specimen type and probes ordered. Testing will be delayed if probe and clinical diagnosis are not provided. Paraffin-embedded specimens and clotted specimens are unacceptable.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 57802-1 - Chrom analy interphase Bld/Mar FISH-Imp
- 11526-1 - Pathology study
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
3 mL (Min: 1 mL)
Minimum Volume
1 mL
Container
green (sodium heparin) tube or heparinized syringe
Collection Instructions
Collect non‑diluted bone marrow aspirate in a heparinized syringe or green (sodium heparin) tube. Transfer 3 mL bone marrow (Min: 1 mL).
Storage Instructions
Room temperature
Causes for Rejection
Paraffin‑embedded specimens. Clotted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant