Histoplasma Antigen Quantitative by EIA, Serum
Also known as: HISTOAG S
Use
This test aids in the diagnosis of histoplasmosis, an infection caused by the fungus Histoplasma capsulatum. It is particularly useful for detecting the presence of histoplasma antigen in serum, which can indicate an active infection. The test employs a quantitative enzyme immunoassay (EIA) to measure antigen concentrations within the range of 0.19 to 60.0 ng/mL. Results outside this range cannot be accurately quantified. In the context of a positive test, cross-reactivity with other fungi such as Blastomyces dermatitidis, Coccidioides immitis, and possibly Talaromyces marneffei should be considered.
Special Instructions
Not provided.
Limitations
Results outside the quantitative range (less than 0.19 ng/mL or greater than 60.0 ng/mL) cannot be accurately quantified. Cross-reactivity with other mycoses, which are endemic in certain geographical regions, may lead to false-positive results. This test should not be the sole basis for diagnosing histoplasmosis and should be used alongside other diagnostic methods.
Methodology
Immunoassay (EIA)
Biomarkers
Histoplasma Antigen
Analyte
LOINC Codes
- 51753-2 - H capsul Ag Ser IA-mCnc
- 44525-4 - H capsul Ag Ser Ql IA
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP Sterile Transport Tube (ARUP Supply #43115)
Collection Instructions
Collect in plain red or serum separator tube (SST).
Storage Instructions
Refrigerated.
Causes for Rejection
Specimen types other than those listed.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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