Histoplasma capsulatum Antibodies Complement Fixation and Immunodiffusion
Use
This test is used for the detection of Histoplasma capsulatum antibodies. It involves the use of complement fixation (CF) and immunodiffusion (ID) methods to help identify active infections with Histoplasma capsulatum, which is a fungus that can cause histoplasmosis. CF titers of ≥1:8 with positive ID results (M or H band) are suggestive of active infection, while CF titers of ≥1:32 are strongly suggestive of active infection. This test provides useful information for diagnosing and managing patients suspected of having acute or chronic histoplasmosis.
Special Instructions
The test requires 1 mL of serum collected in a red-top tube or gel-barrier tube. Proper refrigeration is necessary to maintain the specimen's stability during transportation and storage.
Limitations
This test has not been cleared or approved by the FDA. It was developed and its performance characteristics were determined by LabCorp. Results should be interpreted in conjunction with other clinical and diagnostic information for an accurate assessment.
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 90227-0
- 20573-2
- 20574-0
- 6816-3
Result Turnaround Time
2-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.6 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |
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