Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA, Reflexive Panel
Also known as: HIV PANEL
Use
This test is part of a recommended HIV laboratory testing algorithm, the fourth generation test combination detects HIV antigens and antibodies which enhances early detection of infection. The test detects HIV-1 groups M and O, and HIV-2 as well as the p24 antigen. Repeatedly reactive results will lead to differentiation testing for specific HIV antibodies. Additionally, negative or indeterminate differentiation assay results will reflex to qualitative nucleic acid testing for further confirmation, allowing comprehensive evaluation for HIV-1 and HIV-2 presence.
Special Instructions
This assay should not be used for blood donor screening, associated reentry protocols, or for screening human cells, tissues, and cellular and tissue-based products (HCT/P). The results from this test cannot distinguish between the presence of HIV-1 p24 antigen, HIV-1 antibodies (Groups M/O), or HIV-2 antibodies. Further reflexive testing will incur additional charges.
Limitations
The test cannot be used for donor screening or similar scenarios and the results should not be the sole basis for diagnosis of HIV infection. Reflex testing, as warranted by reactive or indeterminate results on initial screenings, is necessary to confirm diagnosis.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 56888-1
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
2.3 mL
Container
ARUP standard transport tube
Collection Instructions
Separate from cells within 24 hours of collection.
Storage Instructions
SHIP FROZEN.
Causes for Rejection
Heparinized or citrated plasma specimens. Specimens containing particulate material. Severely hemolyzed or heat-inactivated specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 5 days |
| Frozen | 6 weeks |