Immunoglobulin G, CSF
Also known as: IGGCSF
Use
This test aids in the diagnosis of immune-mediated disorders affecting the nervous system by quantifying the level of Immunoglobulin G (IgG) in cerebrospinal fluid (CSF). An abnormal IgG level in CSF can indicate conditions such as multiple sclerosis and other autoimmune disorders affecting the brain and spinal cord. It helps in understanding the central nervous system's immune activity.
Special Instructions
Blood contamination can falsely elevate the CSF IgG concentration, so grossly bloody samples are not acceptable for testing. Proper specimen handling and transport are crucial for accurate results.
Limitations
This test measures only the IgG concentration in CSF and does not provide information about the specific underlying conditions that may cause an abnormal result. Additional clinical information and diagnostic tests are necessary for a comprehensive diagnosis. Hemolyzed specimens may interfere with the immunoturbidimetric method used to quantify IgG.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2464-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge and separate to remove cellular material before transferring to the transport tube.
Causes for Rejection
Grossly bloody or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 month |
| Frozen | 6 months |