Immunoglobulin M, CSF
Also known as: IGM CSF
Use
This test aids in the diagnosis of immune-related disorders affecting the nervous system. It measures the concentration of Immunoglobulin M (IgM) in cerebrospinal fluid (CSF), providing valuable information for distinguishing between different neurological disorders that may present with similar clinical symptoms. Elevated levels of IgM in CSF can indicate an ongoing immune response or inflammation within the central nervous system.
Special Instructions
Collect cerebrospinal fluid (CSF) and ensure proper sample preparation by centrifuging and separating to remove cellular material. Transfer 1 mL of CSF into an ARUP Standard Transport Tube with a minimum volume of 0.5 mL. Avoid grossly bloody or hemolyzed specimens as they are unacceptable for testing.
Limitations
The measurement of IgM in CSF is done using quantitative immunoturbidimetry, which may not detect extremely low levels of IgM that are below the assay's detection limit. Additionally, this test is susceptible to interference from hemolyzed or contaminated samples, which may lead to inaccurate results. Stability of the specimen needs to be maintained, as samples are unstable when kept at ambient temperatures.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2471-1
- 2471-1
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge and separate to remove cellular material. Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Causes for Rejection
Grossly bloody or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 month |
| Frozen | 6 months |