Lysozyme (Muramidase) by Immunohistochemistry
Also known as: LYSOZY IHC
Use
This test is performed as an immunohistochemical stain (technical service) for detection of lysozyme (muramidase) in tissue or cell specimens, aiding in histopathologic evaluation of tissues, particularly in identifying histiocytic/myeloid differentiation patterns. Its results inform diagnostic interpretation of tissue sections using morphological context.
Special Instructions
Submit using electronic request or ARUP Immunohistochemistry Stain Form (#32978) if electronic ordering is unavailable; requires ARUP client number. Refer to ARUP Immunohistochemistry Stain Offerings brochure. This is a stain-and-return (technical) service only.
Limitations
Specimens must be formalin-fixed (10% neutral buffered formalin) and paraffin-embedded or prepared into cellblocks. Unacceptable conditions: non-representative tissue, depleted specimens. If sending precut slides, do not oven bake. Stability: ambient and refrigerated indefinitely; frozen unacceptable.
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Tissue block or 5 unstained (3- to 5‑micron thick) positively charged slides in tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix and paraffin embed specimen (or prepare cells into cellblock). Do not oven bake slides.
Storage Instructions
Transport at room temperature or refrigerated; ship in cooled container during summer.
Causes for Rejection
Non‑representative tissue type; depleted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
