Methylmalonic Acid, Serum or Plasma (Metabolic Disorders)
Also known as: MMA METD
Use
This test is used to evaluate and monitor methylmalonic acidemia, which is a metabolic disorder that can result from vitamin B12 deficiency, renal insufficiency, or inborn errors of metabolism. Measurement of methylmalonic acid levels in serum or plasma helps in diagnosing and assessing the severity of these conditions.
Special Instructions
Not provided.
Limitations
The test has not been cleared or approved by the US Food and Drug Administration and is intended for clinical purposes as a Laboratory Developed Test performed in a CLIA certified laboratory.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
Methylmalonic Acid
Analyte
LOINC Codes
- 13964-2 - Methylmalonate SerPl-sCnc
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.0 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Centrifuge and remove serum or plasma from cells within 2 hours of collection. Immediately transfer to an ARUP standard transport tube and refrigerate or freeze.
Storage Instructions
Refrigerate or freeze immediately after separation from cells.
Causes for Rejection
Specimens stored at room temperature are unacceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 1 week |
| Frozen | 1 month |
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