P57 by Immunohistochemistry
Also known as: P57 IHC
Use
The P57 by Immunohistochemistry test is primarily utilized in the diagnosis and differentiation of Gestational Trophoblastic Disease. This condition can present as different types of molar pregnancies, and the p57 immunostaining is used to help distinguish between partial and complete moles. The presence or absence of p57 expression can provide valuable information due to its distinct pattern in these conditions, which aids in the accurate diagnosis and subsequent management of affected patients.
Special Instructions
Not provided.
Limitations
This test has been classified as a Laboratory Developed Test (LDT) and has not been cleared or approved by the US Food and Drug Administration. As a result, it is only performed in a CLIA certified laboratory for clinical purposes and is intended as a technical stain and return service. It should be noted that any specimens with non-representative tissue types or depleted samples are deemed unacceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
p57
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained slides in a tissue transport kit.
Storage Instructions
Ship at room temperature or refrigerated; use a cooled container during summer.
Causes for Rejection
Non-representative tissue type; depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant