Parvovirus B19 Antibodies, IgG and IgM
Also known as: PARVO
Use
This test aids in the diagnosis of parvovirus infection by detecting the presence of Parvovirus B19 antibodies, IgG, and IgM. The presence of IgG antibodies may indicate current or past infection, while IgM antibodies suggest a more recent or active infection. Monitoring both IgG and IgM antibodies can help distinguish between acute and convalescent stages of infection, especially when supported by appropriately timed specimens as part of a serial testing strategy.
Special Instructions
Not provided.
Limitations
The test may yield equivocal results, requiring repeat testing in 7-21 days. Low levels of IgM antibodies can persist for over 12 months post-infection, potentially affecting the interpretation of current infection. Testing immediately after exposure is of limited value unless followed by convalescent specimen collection. The assay requires that specimens are appropriately timed and handled to avoid bacterial contamination, hemolysis, lipemia, or other unacceptable conditions.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Parvovirus B19 Antibody IgG
ProteinParvovirus B19 Antibody IgM
Protein
LOINC Codes
- 5273-8 - B19V IgG Ser IA-aCnc
- 5274-6 - B19V IgM Ser IA-aCnc
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Serum separator tube (SST)
Collection Instructions
Separate serum from cells as soon as possible, ideally within 2 hours of collection, and transfer to ARUP standard transport tube.
Storage Instructions
Refrigerated transport is necessary. Avoid repeated freeze/thaw cycles.
Causes for Rejection
Unacceptable conditions include bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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