Plasminogen Activator Inhibitor-1, PAI-1 (SERPINE1) Genotyping
Also known as: PAI-1 GENO
Use
This test screens for genetic susceptibility to venous thromboembolism (VTE) or myocardial infarction (MI) in individuals with a personal or family history of thrombotic events. It assists in the risk/benefit assessment for preventive or therapeutic interventions targeting VTE or MI.
Special Instructions
Not provided.
Limitations
The test evaluates only the PAI-1 promoter 4G/5G polymorphism and does not assess other variants within the PAI-1 (SERPINE1) gene. Diagnostic errors can occur due to rare sequence variations, and the test's clinical sensitivity is unknown.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
No genes
Gene
LOINC Codes
- 60577-4 - SERPINE1 gene Mut Anl Bld/T
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
3 mL
Minimum Volume
1 mL
Container
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B)
Storage Instructions
Preferred transport temp: Refrigerated.
Causes for Rejection
Frozen specimens in glass collection tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 1 week |
| Frozen | 1 month |
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