Propoxyphene and Metabolite, Urine
Also known as: PROPOX U
Use
The Propoxyphene and Metabolite, Urine test is utilized to monitor patient adherence to prescribed medications, specifically testing for the presence of propoxyphene and its primary metabolite, norpropoxyphene, in urine. This test helps to ensure patient compliance and aids in the therapeutic management of individuals prescribed this medication. It serves as a diagnostic tool for clinicians to evaluate drug levels within the system and adjust treatment protocols accordingly.
Special Instructions
Specimens for this test should be collected with appropriate care, ensuring that 2 mL of urine is transferred to an ARUP Standard Transport Tube. It's important to note that the test is not performed at ARUP Laboratories but rather by a non-ARUP laboratory. Thus, separate specimens must be submitted if multiple tests are ordered concurrently. Additionally, handling precautions must be observed to avoid interference from substances such as amitriptyline.
Limitations
The test for Propoxyphene and Metabolite is limited by potential interferences, such as the presence of amitriptyline, which can affect the accuracy in quantifying drug levels. It relies on the methodological accuracy of the performing laboratory and the stability of samples during transport and storage. Degradation or contamination can lead to false readings. Furthermore, this test does not provide comprehensive information on drug metabolism beyond measuring specific metabolites and can be influenced by the patient's metabolic rate and kidney function.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 19635-2
- 3545-1
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
2 mL
Minimum Volume
0.7 mL
Container
ARUP Standard Transport Tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 1 week |
| Frozen | 3 months |
