Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA
Also known as: TYPHU G
Use
The Rickettsia typhi (Typhus Fever) Antibody, IgG test is used to confirm the presence of antibodies against Rickettsia typhi, which indicates Typhus Fever. The test is part of a panel that includes both IgG and IgM, and it assists in the diagnosis of Typhus Fever. A significant rise in antibody titers between acute and convalescent serum samples is strong evidence of recent Rickettsia typhi infection. This test helps in identifying group-reactive antibodies for the Typhus Fever group, including Rickettsia prowazekii.
Special Instructions
Parallel testing is recommended. Ensure convalescent specimens are marked and received within 30 days of the acute specimens. Order the panel test (IgG and IgM) when possible for better diagnostic clarity.
Limitations
Results from a single specimen can provide limited clinical information. Ideally, specimens should be tested simultaneously in the same laboratory. It is crucial to submit both acute and convalescent phase samples for accurate diagnosis, which involves detecting a fourfold change in antibody titer. Contaminated, hemolyzed, or severely lipemic specimens may affect test results.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 5324-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Serum Separator Tube (SST)
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |