Toxoplasma gondii Antibody, IgA by ELISA, Serum
Also known as: TOXOG IGA
Use
The Toxoplasma gondii Antibody, IgA by ELISA test is used primarily to aid in the diagnosis of congenital toxoplasmosis in neonates. IgA antibodies are regarded as a more sensitive marker for detecting infection in fetuses and newborns than IgM antibodies. The test results should be interpreted in conjunction with other tests within the Toxoplasma serologic panel to ascertain the clinical significance. This test is only advised to be used in neonates for suspected cases of toxoplasmosis.
Special Instructions
The test is not performed at ARUP Laboratories; therefore, separate specimens must be collected if multiple tests are ordered. The specimen should be refrigerated during transport, but freezing is also acceptable for storage. Care should be taken to avoid gross hemolysis, icterus, lipemia, or bacterial contamination in the specimens provided.
Limitations
The test's utility is limited when not used in conjunction with other tests in the Toxoplasma serologic panel. IgA antibodies in adults can persist for months or even years following an acute infection, which can impact the test's diagnostic clarity. In the event of a positive IgA result in samples taken just after birth, follow-up testing 10 days later is recommended to exclude maternal antibody contamination.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 10723-5
Result Turnaround Time
5-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
0.5 mL
Container
Plain red or serum separator tube (SST)
Storage Instructions
Refrigerated; also acceptable if frozen.
Causes for Rejection
Grossly hemolyzed, icteric, lipemic, and bacterially contaminated specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | Indefinitely |