Treponema pallidum Antibody, IgG by ELISA

Casandra

Casandra Test Code AR16168Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0050920CPT Code 86780

Treponema pallidum Antibody, IgG by ELISA

Also known as: SYPH G

Clinical Use

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Use

The Treponema pallidum Antibody, IgG by ELISA test is recommended for syphilis screening. It detects the presence of IgG antibodies to Treponema pallidum, indicating current or past infection. The test can identify patients who may require further confirmatory testing, such as the Rapid Plasma Reagin (RPR) or the Treponema pallidum Antibody by Particle Agglutination for positive results. The test is part of a reverse syphilis screening algorithm and is New York state approved.

Special Instructions

For optimal results, it is recommended to separate the serum from cells as soon as possible, preferably within 2 hours of collection. A Serum Separator Tube (SST) should be used for specimen collection. This test is approved for use in New York and follows a reverse syphilis screening algorithm.

Limitations

The test is performed as a semi-quantitative enzyme-linked immunosorbent assay and may not be definitive for diagnosing current infection. Equivocal results should be followed by repeat testing in 10-14 days for a more accurate diagnosis. The use of non-serum specimens, such as plasma or other body fluids, may result in unacceptable conditions and are therefore contraindicated. The test's accuracy is dependent on the stability of the specimen, which should not be hemolyzed, lipemic, or contaminated. Repeated freeze/thaw cycles should be avoided to maintain specimen integrity.

Test Details

New York Approved