Treponema pallidum Antibody, IgG by ELISA
Also known as: SYPH G
Use
The Treponema pallidum Antibody, IgG by ELISA test is recommended for syphilis screening. It detects the presence of IgG antibodies to Treponema pallidum, indicating current or past infection. The test can identify patients who may require further confirmatory testing, such as the Rapid Plasma Reagin (RPR) or the Treponema pallidum Antibody by Particle Agglutination for positive results. The test is part of a reverse syphilis screening algorithm and is New York state approved.
Special Instructions
Not provided.
Limitations
The test is performed as a semi-quantitative enzyme-linked immunosorbent assay and may not be definitive for diagnosing current infection. Equivocal results should be followed by repeat testing in 10-14 days for a more accurate diagnosis. The use of non-serum specimens, such as plasma or other body fluids, may result in unacceptable conditions and are therefore contraindicated. The test's accuracy is dependent on the stability of the specimen, which should not be hemolyzed, lipemic, or contaminated. Repeated freeze/thaw cycles should be avoided to maintain specimen integrity.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Treponema pallidum IgG Antibody
Protein
LOINC Codes
- 51838-1 - T palldm IgG Ser IA-aCnc
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells as soon as possible or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Plasma or other body fluids, contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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