West Nile Virus Antibody, IgG by ELISA, Serum
Also known as: WNILE IGG
Use
This test is used as a semi-quantitative method to detect West Nile virus-specific IgG in serum specimens where there is a clinical suspicion of West Nile virus infection. It should not be used solely for quantitative purposes, nor should the results be used without correlation with clinical history or other data. A seroconversion between acute and convalescent sera is considered strong evidence of current or recent infection. The test is designed to identify past infection or exposure rather than diagnosing acute West Nile infection.
Special Instructions
The test is not recommended for diagnosing acute West Nile infection. Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens as 'acute' or 'convalescent' plainly.
Limitations
Other members of the Flaviviridae family, such as St. Louis encephalitis virus, exhibit extensive cross-reactivity with West Nile virus. Therefore, serologic testing specific for these species should be considered. The best evidence for infection is a significant change in two appropriately timed specimens, both tested in the same laboratory at the same time.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 38997-3
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer to ARUP Standard Transport Tube. Parallel testing is preferred with convalescent specimens to be received within 30 days from receipt of the acute specimens.
Storage Instructions
Refrigerated. Avoid repeated freeze/thaw cycles.
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |