Hereditary Neuropathy Panel

Casandra

Casandra Test Code GE18613Version 1 (DRAFT)

Performing Lab

Lab GeneDxLab Test ID 737

Hereditary Neuropathy Panel

Clinical Use

Use

This test is a comprehensive gene sequencing and deletion/duplication analysis of 89 genes associated with hereditary neuropathies, intended for diagnostic evaluation of individuals with suspected inherited neuropathy syndromes (GeneDx Neurology Test Requisition; Test Code 737)

Special Instructions

Ordering includes an option for New York retention—patients who are New York State residents may opt-in to allow GeneDx to retain remaining sample for longer than 60 days post‑testing (NY Retention Opt‑In checkbox)

Limitations

GeneDx frequently updates gene content; the specific gene list and technical limitations may change and users are referred to the GeneDx website for the most current information (as noted on the Neurology Test Requisition Form)

Test Details

Methodology

NGS (Targeted)

Biomarkers

Mutation (89 genes)

AARSABHD12AIFM1ATL1ATL3ATP7ABAG3BICD2BSCL2CHCHD10CNTNAP1COX6A1CYP27A1DNAJB2DNM2DNMT1DSTDYNC1H1EGR2ELP1RETREG1FBXO38FGD4FIG4GANGARSGDAP1GJB1GLAGNB4HADHAHARSHINT1HSPB1HSPB8IGHMBP2INF2KARSKIF1AKIF5ALITAFLMNALRSAM1MFN2MMEMORC2MPV17MPZMTMR2NDRG1NEFHNEFLNGFNTRK1PDK3PLEKHG5PMP22PNKPPRDM12PRPS1PRXRAB7AREEP1SBF1SBF2SCN11ASCN9ASCO2SEPT9SETXSH3TC2SIGMAR1SLC12A6SLC25A46SLC52A2SLC52A3SLC5A7SPG11SPTLC1SPTLC2TFGTRIM2TRPV4TTRVAPBVCPVRK1WNK1YARS