Adrenocorticotropic Hormone (ACTH), Plasma, Eight Specimens
Use
The Adrenocorticotropic Hormone (ACTH) Plasma test is used to diagnose or rule out conditions related to abnormal hormone levels, such as Cushing's disease and Addison's disease. The test is generally ordered as part of a series for dynamic endocrine testing, which requires drawing multiple specimens over time to evaluate the patient's response to a stimulus, such as a medication or a physiological challenge. Monitoring ACTH levels can help guide treatment and management of disorders affecting the pituitary gland or adrenal glands.
Special Instructions
Not provided.
Limitations
This test may not be accurate for patients currently taking or recently having taken biotin supplements, as high doses can interfere with the assay results. Proper timing and adherence to specimen collection procedures are crucial for reliable results. The test also requires careful handling and processing of multiple time-point specimens, which may introduce variability if not managed correctly.
Methodology
Immunoassay (CLIA)
Biomarkers
Adrenocorticotropic Hormone
Analyte
LOINC Codes
- 42598-3 - ACTH BS Plas-mCnc
- 42598-3 - ACTH BS Plas-mCnc
- 39564-0 - ACTH sp1 p chal Plas-mCnc
- 12458-6 - ACTH sp2 p chal Plas-mCnc
- 12459-4 - ACTH sp3 p chal Plas-mCnc
- 12460-2 - ACTH sp4 p chal Plas-mCnc
- 12461-0 - ACTH sp5 p chal Plas-mCnc
- 12462-8 - ACTH sp6 p chal Plas-mCnc
- 12463-6 - ACTH sp7 p chal Plas-mCnc
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Special ACTH tube
Collection Instructions
Collect blood in a special ACTH tube. Multiple specimens should be collected at specific time intervals as prescribed. Ensure tubes are labeled in sequence and transport them promptly to the laboratory.
Patient Preparation
Patients should discontinue biotin supplements at least 72 hours prior to specimen collection.
Storage Instructions
Plasma should be separated and frozen if not immediately transported to the lab.
Causes for Rejection
Specimens collected from patients consuming high doses of biotin.
Other tests from different labs that may be relevant