Anti-Dense Fine Speckled Protein 70 kDa (DFS70) Ab
Also known as: Anti-dense fine speckled, DFS70/LEDGFp75, LEDGFp75, Lens Epithelium-derived Growth Factor or transcription co-activator p75, SARD exclusion marker
Use
Anti-DFS70 antibodies may help identify individuals who do not have an ANA-associated Autoimmune Rheumatic Disease (AARD) especially in the absence of significant clinical findings.1 Anti-DFS70 Ab, especially when positive in isolation (i.e. in the absence of AARD-associated autoantibodies), may prevent unnecessary referrals and examinations of ANA-positive individuals.2
Special Instructions
Not provided.
Limitations
This test should be used with clinical findings and other autoimmune testing; it cannot be used alone to rule out autoimmune disease. Anti-DFS70 antibodies are detectable in 2% to 22% of healthy individuals and in less than 1% of patients with AARD and are of unknown clinical significance.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 95129-3
- 95129-3
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube; serum from red-top tube; serum from a gel tube; or serum gel tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |