Anti-DNase B (Streptococcal) Antibodies
Also known as: ADB, Anti-DNase B Antibodies, DNase-B, DNase-B Antibodies, Streptococcal Antibodies
Use
Provides evidence of an existing or past streptococcal infection
Special Instructions
The antibody reaction against streptococcal DNase B starts later than the antibody production against streptolysin O, but it can then be detected on a greater percentage of patients. This test's relevance is particularly noted in cases where skin infections are suspected, with a rise in ADNase B titer being observable.
Limitations
An increase in the antistreptolysin concentration rarely occurs with skin infections, whereas a rise in the ADNase B titer can be observed. Results must be interpreted in the context of other clinical and laboratory findings. Gross lipemia that cannot be clarified by ultracentrifugation and severely hemolyzed or heat-inactivated samples are causes for rejection.
Methodology
Immunoassay (Immunonephelometry)
Biomarkers
LOINC Codes
- 5133-4
- 5133-4
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Gross lipemia that cannot be clarified by ultracentrifugation; heat-inactivated samples; severe hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 9 days |
| Refrigerated | 14 days |
| Frozen | 14 days |