Anti-ENA Abs (RDL)
Also known as: Anti-Extractable Nuclear Antigen Antibodies
Use
Aids in the diagnosis of Systemic Lupus Erythematosus (SLE), and related connective tissue diseases such as Sjogren's Syndrome. Anti-Sm is highly specific for SLE. Anti U1-RNP is found with a varitey of rheumatoid diseases with high titers associated mainly with MCTD.
Special Instructions
Not provided.
Limitations
The test results should be interpreted in conjunction with other clinical and laboratory findings. The specificities for Anti-Sm and Anti-U1 RNP antibodies have clinical significance but their presence alone is not diagnostic of a specific disease. Further clinical correlation is essential.
Methodology
Immunoassay (ELISA)
Biomarkers
Anti-Sm
ProteinAnti-U1 RNP
Protein
LOINC Codes
- 11090-8 - ENA SM Ab Ser-aCnc
- 57662-9 - U1 snRNP Ab Ser IA-aCnc
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |
Other tests from different labs that may be relevant