Anti-U1 RNP Ab (RDL)
Also known as: Anti-RNP
Use
Anti-U1 RNP antibodies typically appear in both SLE and MCTD. In MCTD, the presence of U1 RNP is required for diagnosis, whereas anti-RNP antibodies occur in only 30-40% of SLE. MCTD is typified by the high-titer RNP antibody activity in isolation; anti-RNP antibody activity in SLE commonly accompanies anti-Sm antibodies.
Special Instructions
Separate serum from cells within one hour of collection and transfer to a plastic transport tube before shipping. Submit separate frozen specimens for each test requested to avoid delays in turnaround time when requesting multiple tests on frozen samples.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration. The presence of gross hemolysis, bacterial contamination, lipemic specimens, icteric specimens, or non-serum specimen types may cause rejection of the sample.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 53022-0
- 57662-9
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |