Anticardiolipin Antibodies (ACA), IgA, IgG, IgM, Quantitative
Also known as: Antiphospholipids, Cardiolipin Antibodies
Use
Anticardiolipin antibodies are often present in individuals with the antiphospholipid antibody syndrome.1,2
Special Instructions
Not provided.
Limitations
ACA can appear during acute bacterial or viral infections and in individuals with syphilis, often transient and not linked with increased clinical complication risk. Most are transient and don't indicate APS. False positives can occur, necessitating retesting for definitive diagnosis. Conditions like autoimmune disorders and malignancies can feature ACA, increasing APS risk. Drugs can induce ACA with potential clinical significance if persistent.
Methodology
Immunoassay (ELISA)
Biomarkers
Anticardiolipin Antibody IgA
ProteinAnticardiolipin Antibody IgG
ProteinAnticardiolipin Antibody IgM
Protein
LOINC Codes
- 3180-7 - Cardiolipin Ab Ser IA-aCnc
- 3181-5 - Cardiolipin IgG Ser IA-aCnc
- 3182-3 - Cardiolipin IgM Ser IA-aCnc
- 5076-5 - Cardiolipin IgA Ser IA-aCnc
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate
Causes for Rejection
Hemolysis; lipemia; icteric specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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