Complement C1 Esterase Inhibitor, Functional
Also known as: C1 Esterase Inhibitor, C1 Inactivator, C1 Inhibitor, Esterase Inhibitor, Hereditary Angioneurotic Edema Test
Use
Esterase inhibitor is decreased in hereditary angioneurotic edema. Functional level will be decreased when concentration of inhibitor is decreased or inhibitor is nonfunctional.
Special Instructions
For accurate results, it is important to separate serum or plasma from cells and transfer it to a plastic transport tube before freezing. When multiple tests are requested on frozen samples, separate frozen specimens should be submitted for each test to avoid delays in turnaround time.
Limitations
The test may not accurately differentiate between hereditary and acquired deficiency states. Additionally, other factors such as improper sample handling may affect the reliability of test results. Thawed or nonfrozen samples, as well as plasma other than EDTA, are causes for rejection, which may necessitate resubmission of samples.
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 48494-9
- 48494-9
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
Red-top tube
Collection Instructions
Separate serum from cells and transfer to a plastic transport tube before freezing.
Storage Instructions
Freeze. Serum should not be stored at room temperature for longer than six hours.
Causes for Rejection
Plasma other than EDTA; thawed or nonfrozen sample
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 hours |