Copper, Urine
Also known as: Cu, Urine
Use
Monitor exposure to copper
Special Instructions
Request form must state 24-hour collection volume, if applicable. Do not use preservatives, as they may contain substances like mercuric oxide, which interfere with metal testing. Separate urine specimen is required if both urinalysis and metal testing are ordered.
Limitations
Increased urinary copper excretion can arise in conditions such as intrahepatic cholestasis of pregnancy (ICC) or chronic active hepatitis. Wilson's disease and chronic active hepatitis may present similar urinary copper levels; thus, additional assessments like ceruloplasmin and serum copper are recommended for differentiation.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 5632-5
- 2161-8
- 13829-7
- 5633-3
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
1.3 mL
Container
Plastic urine container, no preservative
Collection Instructions
Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |